12 Queen Square

 

 

 

Dr Rosalyn Moran

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London

 

 

Rosalyn Moran

 

Current Research: Theoretical Neurobiology & Imaging Neuroscience

My research employs both theoretical and empirical neuroscientific approaches to understand the principles of functional integration in the brain and in particular how neuromodulators shape the dynamics of neuronal communication in health and disease. In relating the macroscopic measures from functional neuroimaging and electrophysiological investigations (including functional Magnetic Resonance Imaging (fMRI), electroencephalography (EEG), magnetoencephalography (MEG) and local field potentials), to their chemical substrates through models of cortical circuits, my research aims to define and refine the mechanisms underlying human cognition.

This approach takes a particular form, namely, dynamic causal modelling (DCM), which uses variational bayesian techniques, with linear and nonlinear dynamical systems theory, to infer model based physiological processes from empirical data. I apply this approach to human and animal data, examining the interaction of dopamine, acetylcholine and serotonin with ongoing neural activity. Encompassing multiple levels of description, DCM provides a platform by which animal and human probes can be cross-interpreted and translated. One example of this, is in the study of neurodegenerative disease, where the characterisation of pathological circuits in Parkinsonian animal models has informed human circuit analysis in patient populations.

I work in the groups of Professor Karl Friston (Theroretical Neurobiology and Methods) and Professor Ray Dolan (Emotion and Decision Making) as a Senior Research Associate at the Wellcome Trust Centre for Neuroimaging. My research is supported by the Max Planck Society and the Wellcome Trust.

Publications

Neurobiology

Methodology

Other

 

PDFs are available by clicking on the title

 

Education

PhD Electronic Engineering, University College Dublin

Postdoctoral Fellowship, Wellcome Trust Centre for Neuroimaging, Univeristy College London

 

Links

Upcoming Talks & Courses

Tube SPM

ION Short Course on Statistical Parametric Mapping,

London

fMRI SPM Course Zurich

MEG/EEG SPM Course Lyons

 

Links

 
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Brain Connectivity Workshop 2012, June 6-8, Chengdu, China

Link

 

Aliquam aliquet semThe Fields Institute
for Research in Mathematical Sciences

University of Toronto

Focus Program on "Towards Mathematical Modeling of Neurological Disease from Cellular Perspectives"

Parkinson's Disease Workshop, May 22-23, 2012

Link
FEP

A Short Course on the Free Energy Principle,

FIL, London July 5th-6th, 2012