function out = spm_run_dcm_bms(job)
% Compare DCMs on the basis of their log-evidences
% Four methods are available to identify the best among alternative models:
%
%  (1) single subject BMS using Bayes factors
%      (see Penny et al, NeuroImage, 2004)
%  (2) fixed effects group BMS using group Bayes factors
%      (see Stephan et al, NeuroImage, 2007)
%  (3) random effects group BMS using exceedance probabilities
%      (see Stephan et al, NeuroImage, 2009)
%  (4) comparing model families
%      (see Penny et al, PLOS-CB, 2010)
%
% Note: All functions use the negative free energy (F) as an approximation
% to the log model evidence.
%__________________________________________________________________________
% Copyright (C) 2009-2014 Wellcome Trust Centre for Neuroimaging

% CC Chen & Maria Joao Rosa
% $Id: spm_run_dcm_bms.m 6442 2015-05-21 09:13:44Z will $


SVNid = '$Rev: 6442 $';

%-Say hello
%--------------------------------------------------------------------------
spm('FnBanner',mfilename,SVNid);

%-Input parameters
%--------------------------------------------------------------------------
fname   = 'BMS.mat';                     % Output filename
fname   = fullfile(job.dir{1},fname);    % Output filename (inc. directory)
ld_f    = ~isempty(job.load_f{1});       % Log-evidence file
ld_msp  = ~isempty(job.model_sp{1});     % Model space file
bma_do  = isfield(job.bma,'bma_yes');    % Compute BMA
data_se = ~isempty(job.sess_dcm);        % DCM files

out.bmsmat = {''};

% check whether a BMS.mat file exists in the selected directory
if exist(fname,'file')
    str = {'Current directory contains a BMS file:',...
        'Continuing will overwrite existing file !!'};
    if spm_input(str,1,'bd','stop|continue',[1,0],1,mfilename);
        fprintf('%-40s: %30s\n\n',...
            'BMS stoped...existing BMS file in the selected directory',...
            spm('time'));
        Fgraph  = spm_figure('GetWin','Graphics');
        spm_clf(Fgraph);
        return
    end
end

%-Method
% -------------------------------------------------------------------------
if strcmp(job.method,'FFX');
    method = 'FFX';                      % Fixed-effects
else
    method = 'RFX';                      % Random-effects
end

%-Check DCM.mat files and BMA
%--------------------------------------------------------------------------
do_bma_famwin = 0;
do_bma_all    = 0;

if bma_do
    if ld_msp
        fprintf('%-40s: ','Loading model space')                        %-#
        load(job.model_sp{1});
        load(subj(1).sess(1).model(1).fname)
        fprintf('%30s\n','...done')                                     %-#
    else
        if data_se
            load(job.sess_dcm{1}(1).dcmmat{1})
        else
            spm('alert','Please specify DCM.mat files or model_space.mat to do BMA!','Error');
            return
        end
    end
    
    nsamp       = 1e4;
    odds_ratio  = 1/20;
    
    if isfield(job.bma.bma_yes,'bma_famwin')
        do_bma_famwin  = 1;
    else
        if isfield(job.bma.bma_yes,'bma_all')
            do_bma_all = 1;
        else
            bma_fam    = double(job.bma.bma_yes.bma_part);
        end
    end
else
    if ld_msp
        fprintf('%-40s: ','Loading model space')                        %-#
        load(job.model_sp{1});
        fprintf('%30s\n','...done')                                     %-#
        if ~exist('subj','var')
            spm('alert','Incorrect model space file! File must contain ''subj'' structure.','Error');
            return
        end
    end
end

%-Initialise
%--------------------------------------------------------------------------
F      = [];                % Free energy
N      = {};                % Models

%-Prepare the data
%--------------------------------------------------------------------------
if  ld_f
    data      = job.load_f{1};
    load(data);
    nm        = size(F,2);                                % No of Models
    ns        = size(F,1);                                % No of Subjects
    N         = 1:nm;
    subj      = [];                                       % subj structure
    f_fname   = data;                                     % LogE file name
    fname_msp = [];                                       % Model space
    
else
    
    f_fname       = [];                                   % LogE file name
    
    % Verify dimensions of data and model space
    if ld_msp
        ns        = length(subj);                         % No of Subjects
        nsess     = length(subj(1).sess);                 % No of sessions
        nm        = length(subj(1).sess(1).model);        % No of Models
        fname_msp = [job.model_sp{1}];
    else
        ns        = size(job.sess_dcm,2);                 % No of Subjects
        nsess     = size(job.sess_dcm{1},2);              % No of sessions
        nm        = size(job.sess_dcm{1}(1).dcmmat,1);   % No of Models
        fname_msp = fullfile(job.dir{1},'model_space.mat');
    end
    
    F       = zeros(ns,nm);
    N       = cell(nm);
    
    % Check if No of models > 2
    if nm < 2
        spm('alert','Please select more than one file','Error');
        return
    end
    
    for k=1:ns
        
        % Verify dimensions of data and model space for current session
        if ld_msp
            nsess_now       = length(subj(k).sess);
            nmodels         = length(subj(k).sess(1).model);
        else
            disp(sprintf('Loading DCMs for subject %d', k));
            nsess_now       = size(job.sess_dcm{k},2);
            nmodels         = size(job.sess_dcm{k}(1).dcmmat,1);
        end
        
        if (nsess_now == nsess && nmodels== nm) % Check no of sess/mods
            
            ID = zeros(nm,nsess);
            
            for j=1:nm
                
                F_sess      = [];
                
                for h = 1:nsess_now
                    
                    if ~ld_msp
                        
                        clear DCM
                        
                        % Load DCM (model)
                        tmp = job.sess_dcm{k}(h).dcmmat{j};
                        if ~job.verify_id
                            st = warning('off','MATLAB:load:variableNotFound');
                            DCM.DCM = load(tmp, 'F', 'Ep', 'Cp');
                            warning(st);
                            if ~isfield(DCM.DCM, 'F')
                                DCM     = load(tmp);
                            end
                        else
                            DCM     = load(tmp);
                        end
                        
                        % Free energy for sessions
                        F_sess  = [F_sess,DCM.DCM.F];
                        
                        % Create model space
                        subj(k).sess(h).model(j).fname = tmp;
                        subj(k).sess(h).model(j).F     = DCM.DCM.F;
                        subj(k).sess(h).model(j).Ep    = DCM.DCM.Ep;
                        subj(k).sess(h).model(j).Cp    = DCM.DCM.Cp;
                        
                    else
                        
                        tmp = subj(k).sess(h).model(j).fname; 
                        DCM = load(tmp); 
                        F_sess = [F_sess,subj(k).sess(h).model(j).F];
                        
                    end
                    
                    % Data ID verification. At least for now we'll
                    % re-compute the IDs rather than use the ones stored
                    % with the DCM.
                    if ~exist('DCM','var') || ~isfield(DCM,'DCM'), job.verify_id = 0; end
                    if job.verify_id
                        
                        disp(sprintf('Identifying data: model %d', j));
                        
                        M   = DCM.DCM.M;
                        
                        if isfield(DCM.DCM, 'xY')
                            Y = DCM.DCM.xY;  % not fMRI
                        else
                            Y = DCM.DCM.Y;   % fMRI
                        end
                        
                        if isfield(M,'FS')
                            try
                                ID(j,h)  = spm_data_id(feval(M.FS,Y.y,M));
                            catch
                                ID(j,h)  = spm_data_id(feval(M.FS,Y.y));
                            end
                        else
                            ID(j,h) = spm_data_id(Y.y);
                        end
                        
                    end
                end
                
                % Sum over sessions
                F_mod       = sum(F_sess);
                F(k,j)      = F_mod;
                N{j}        = sprintf('model%d',j);
                
            end
            
            if job.verify_id
                failind = find(max(abs(diff(ID)),[],1) > eps);
                if ~isempty(failind)
                    str_error = ['The models for subject ' num2str(k) ...
                        ' session(s) ' num2str(failind) ' were not fitted to the same data.'];
                    spm('alert',str_error,'Error');
                    return
                end
            end
        else
            spm('alert','The number of sessions/models should be the same for all subjects!','Error');
            return         
        end
        
    end
end

%-Bayesian Model Selection
%==========================================================================

% free energy
sumF = sum(F,1);

%-Family or model level
%--------------------------------------------------------------------------
if isfield(job.family_level,'family_file')
    
    if ~isempty(job.family_level.family_file{1})
        
        load(job.family_level.family_file{1});
        do_family    = 1;
        family.infer = method;
        
        nfam    = size(family.names,2);
        npart   = length(unique(family.partition));
        maxpart = max(family.partition);
        m_indx  = 1:nm;
        
        if nfam ~= npart || npart == 1 || maxpart > npart
            spm('alert','Invalid family file!','Error');
            return
        end
    else
        do_family = 0;
    end
    
else
    
    if isempty(job.family_level.family)
        do_family    = 0;
    else
        do_family    = 1;
        nfam         = size(job.family_level.family,2);
        
        names_fam  = {};
        models_fam = [];
        m_indx     = [];
        for f=1:nfam
            names_fam    = [names_fam,job.family_level.family(f).family_name];
            m_indx       = [m_indx,job.family_level.family(f).family_models'];
            models_fam(job.family_level.family(f).family_models) = f;
        end
        
        family.names     = names_fam;
        family.partition = models_fam;
        
        npart   = length(unique(family.partition));
        maxpart = max(family.partition);
        nmodfam = length(m_indx);
        
        if nfam ~= npart || npart == 1 || maxpart > npart || nmodfam > nm
            spm('alert','Invalid family!','Error');
            return
        end
        
        family.infer     = method;
        
    end
    
end

%-Single subject BMS or 1st level (fixed effects) group BMS
%--------------------------------------------------------------------------
if strcmp(method,'FFX')
    
    fprintf('%-40s: ','Computing FFX model/family posteriors')          %-#
    if ~do_family
        family         = [];
        model.post     = spm_api_bmc(sumF,N,[],[]);
    else
        Ffam           = F(:,sort(m_indx));
        [family,model] = spm_compare_families(Ffam,family);
        P              = spm_api_bmc(sumF,N,[],[],family);
    end
    fprintf('%30s\n','...done')                                         %-#
    
    if bma_do
        if do_family
            if do_bma_famwin
                [fam_max,fam_max_i]  = max(family.post);
                indx  = find(family.partition==fam_max_i);
                post  = model.post(indx);
            else
                if do_bma_all
                    post = model.post;
                    indx = 1:nm;
                else
                    if bma_fam <= nfam && bma_fam > 0 && rem(bma_fam,1) == 0
                        indx  = find(family.partition==bma_fam);
                        post  = model.post(indx);
                    else
                        spm('alert','Incorrect family for BMA!','Error');
                        return
                    end
                end
            end
        else
            post  = model.post;
            indx = 1:nm;
        end
        
        %-Bayesian Model Averaging
        %------------------------------------------------------------------
        fprintf('%-40s: ','FFX Bayesian model averaging')               %-#
        bma = spm_dcm_bma(post,indx,subj,nsamp,odds_ratio);
        fprintf('%30s\n','...done')                                     %-#
        
    else
        
        bma = [];
        
    end
    
%     if exist(fullfile(job.dir{1},'BMS.mat'),'file')
%         load(fname);
%         if  isfield(BMS,'DCM') && isfield(BMS.DCM,'ffx')
%             spm('alert','Existing BMS.mat file has been over-written!',...
%                 'Warning');
%         end
%     end
    BMS.DCM.ffx.data    = fname_msp;
    BMS.DCM.ffx.F_fname = f_fname;
    BMS.DCM.ffx.F       = F;
    BMS.DCM.ffx.SF      = sumF;
    BMS.DCM.ffx.model   = model;
    BMS.DCM.ffx.family  = family;
    BMS.DCM.ffx.bma     = bma;
    
% 2nd-level (random effects) BMS
%--------------------------------------------------------------------------
else
    
    fprintf('%-40s: ','Computing RFX model/family posteriors')          %-#
    if ~do_family
        [exp_r,xp,r_samp,g_post] = spm_BMS_gibbs(F);
        model.g_post             = g_post;
        model.alpha = exp_r*(nm+ns);
        model.exp_r = exp_r;
        model.xp    = xp;
        family      = [];
        
        % Compute protected xp's
        posterior.a=model.alpha;
        posterior.r=g_post';
        priors.a=ones(1,nm);
        model.bor = spm_BMS_bor (F',posterior,priors);

        % Compute protected exceedance probs - Eq 7 in Rigoux et al.
        model.pxp=(1-model.bor)*xp+model.bor/nm;
        
    else
        Ffam           = F(:,sort(m_indx));
        [family,model] = spm_compare_families(Ffam,family);
        
    end
    fprintf('%30s\n','...done')                                         %-#
    
    %-Display result
    if do_family
        P = spm_api_bmc(sumF,N,model.exp_r,model.xp,family);
        
    else
        P = spm_api_bmc(sumF,N,model.exp_r,model.xp);
        
        % Plot protected xp's
        nm_tmp = length(N);
        Fpxp  = spm_figure('Create','Graphics','BMS: results ...');
        figure(Fpxp);
        subplot(2,1,1)
        bar(1:length(N),model.pxp(:)')
        set(gca,'XTick',1:length(N))
        set(gca,'XTickLabel',1:nm_tmp)
        ylabel('Protected Exceedance Probability','Fontsize',14)
        xlabel('Models','Fontsize',14)
        title(sprintf('Prob of Equal Model Frequencies (BOR) = %1.2f',model.bor),'Fontsize',14);
        axis square
        grid on
        
    end
    
    if bma_do
        if do_family
            if do_bma_famwin
                [fam_max,fam_max_i]  = max(family.exp_r);
                indx = find(family.partition==fam_max_i);
                post  = model.g_post(:,indx);
            else
                if do_bma_all
                    post = model.g_post;
                    indx = 1:nm;
                else
                    if bma_fam <= nfam && bma_fam > 0 && rem(bma_fam,1) == 0
                        indx = find(family.partition==bma_fam);
                        post = model.g_post(:,indx);
                    else
                        spm('alert','Incorrect family for BMA!','Error');
                        return
                    end
                end
            end
        else
            post  = model.g_post;
            indx = 1:nm;
        end
        
        %-Bayesian Model Averaging
        %------------------------------------------------------------------
        fprintf('%-40s: ','RFX Bayesian model averaging')               %-#
        bma = spm_dcm_bma(post,indx,subj,nsamp,odds_ratio);
        fprintf('%30s\n','...done')                                     %-#
        
    else
        
        bma = [];
        
    end
    
%     if exist(fullfile(job.dir{1},'BMS.mat'),'file')
%         load(fname);
%         if  isfield(BMS,'DCM') && isfield(BMS.DCM,'rfx')
%             spm('alert','Existing BMS.mat file has been over-written!',...
%                 'Warning');
%         end
%     end
    BMS.DCM.rfx.data    = fname_msp;
    BMS.DCM.rfx.F_fname = f_fname;
    BMS.DCM.rfx.F       = F;
    BMS.DCM.rfx.SF      = sumF;
    BMS.DCM.rfx.model   = model;
    BMS.DCM.rfx.family  = family;
    BMS.DCM.rfx.bma     = bma;
    
end

%-Data verification
%--------------------------------------------------------------------------
if job.verify_id
    fprintf('%-40s: %30s\n','Data identity','...verified')              %-#
else
    fprintf('%-40s: %30s\n','Data identity','...not verified')          %-#
end

%-Save BMS.mat
%--------------------------------------------------------------------------
fprintf('%-40s: %30s','Saving BMS.mat','...writing')                    %-#
save(fname,'BMS', spm_get_defaults('mat.format'));
fprintf('%s%30s\n',repmat(sprintf('\b'),1,30),'...done')                %-#

out.bmsmat = { fname };

%-Save model_space
%--------------------------------------------------------------------------
if ~ld_msp && data_se && ~ld_f
    fprintf('%-40s: %30s','Saving model space','...writing')            %-#
    save(fname_msp,'subj', spm_get_defaults('mat.format'));
    fprintf('%s%30s\n',repmat(sprintf('\b'),1,30),'...done')            %-#
    
    out.model_space = { fname_msp };
end
