F Karl Friston FRS FMedSci
Wellcome Principal Research Fellow and
Scientific Director
Wellcome Trust Centre for Neuroimaging
Professor: Institute of Neurology, University College London
Honorary Consultant: The National Hospital for Neurology and Neurosurgery, UK
Bio-sketch
Karl
Friston is a neuroscientist and authority on brain imaging. He invented statistical parametric mapping:
SPM is an international standard for analysing imaging data and rests on the
general linear model and random field theory (developed with Keith
Worsley). In 1994, his group developed
voxel-based morphometry. VBM detects differences in neuroanatomy and is used
clinically and as a surrogate in genetic studies. These technical contributions were motivated
by schizophrenia research and theoretical studies of value-learning (with Gerry
Edelman). In 1995 this work was formulated as the disconnection hypothesis of
schizophrenia (with Chris Frith). In 2003, he invented dynamic causal modelling
(DCM), which is used to infer the architecture of distributed systems like the
brain. Mathematical contributions include variational (generalised) filtering
and dynamic expectation maximization (DEM) for Bayesian model inversion and
time-series analysis. Friston currently works on models of functional
integration in the human brain and the principles that underlie neuronal
interactions. His main contribution to theoretical neurobiology is a
free-energy principle for action and perception (active inference). Friston received the first Young
Investigators Award in Human Brain Mapping (1996) and was elected a Fellow of
the Academy of Medical Sciences (1999) in recognition of contributions to the
bio-medical sciences. In 2000 he was
President of the international Organization of Human Brain Mapping. In 2003 he was awarded the Minerva Golden
Brain Award and was elected a Fellow of the Royal Society in 2006. In 2008 he
received a Medal, Collθge de France and an Honorary Doctorate from the
University of York in 2011. He became of Fellow of the Society of Biology in
2012.
Selected
Publications:
·
Predictive coding and information theory
·
Bayesian and
Variational model inversion
·
Optimality,
value-learning and plasticity
·
Disconnection
hypothesis and schizophrenia
·
Neuroimaging
(reviews and commentaries)
·
Voxel-based
morphometry and computational anatomy
·
Source
reconstruction (EEG and MEG)
Free-energy
principle and the
Bayesian Brain
Key papers
Bastos
AM, Usrey WM, Adams RA, Mangun GR, Fries P, Friston KJ.
Canonical
microcircuits for predictive coding.
Neuron. 2012 Nov 21;76(4):695-711 - pdf
Friston
K.
A Free Energy
Principle for Biological Systems
Entropy
2012, 14, 2100-2121; doi:10.3390/e14112100 - pdf
Adams RA, Shipp S, Friston KJ.
Predictions not
commands: active inference
in the motor system.
Brain Struct Funct. 2012
Nov 6. [Epub ahead of print] -
pdf
Friston
K, Samothrakis S, Montague R.
Active inference
and agency: optimal control without cost functions
Biol Cybern.
2012 DOI: 10.1007/s00422-012-0512-8 - pdf
Hobson
JA, Friston KJ.
Waking and
dreaming consciousness: Neurobiological and functional considerations.
Prog
Neurobiol. 2012 May 15;98(1):82-98 - pdf
Friston
K, Adams RA, Perrinet L and Breakspear M
Perceptions as
hypotheses: saccades as experiments.
Front.
Psychology (2012) 3:151. doi:
10.3389/fpsyg.2012.00151- pdf
Brown
H, Friston KJ.
Free-energy and illusions:
the Cornsweet effect.
Front.
Psychology 2012, 3:43. doi:10.3389/fpsyg.2012.00043 - pdf
Friston
KJ, Shiner T, FitzGerald T, Galea JM, Adams R, et al.
Dopamine, Affordance
and Active Inference.
PLoS
Comput Biol 2012, 8(1): e1002327 - pdf
Friston,
K. Ao, P.
Free-energy, value
and attractors.
Computational
and mathematical methods in medicine, Volume 2012, Article ID 937860 pdf
Friston
K.
Policies and
Priors.
Springer
Series in Computational Neuroscience, 1, Volume 10,
Computational
Neuroscience of Drug Addiction, 2011;Part 3, Pages 237-283
pdf
Friston
K, Mattout J, Kilner J.
Action
understanding and active inference.
Biol
Cybern. 2011 104:137160 pdf
Feldman
H, Friston KJ.
Attention,
uncertainty, and free-energy.
Front
Hum Neurosci. 2010 Dec 2;4:215. pdf
Friston
KJ, Daunizeau J, Kilner J, Kiebel SJ.
Action and
behavior: a free-energy formulation.
Biol
Cybern. 2010 102(3):227-60 pdf
Friston KJ,
Daunizeau J, Kiebel SJ.
Reinforcement learning or active inference?
PLoS One. 2009 Jul
29;4(7):e6421. pdf
Friston K.
Hierarchical
Models in the Brain.
PLoS Comput Biol (2008) 4(11): e1000211. pdf
Friston K, Stephan
KE.
Free energy and the brain.
Synthese. 2007.
159:417458. pdf
Friston K, Kilner
J, Harrison L.
A free energy principle for the brain.
J Physiol Paris.
2006 Jul-Sep;100(1-3):70-87. pdf
Friston K.A theory of cortical responses.
Philos Trans R Soc Lond B Biol Sci. 2005 Apr 29;360(1456):815-36. pdf
Reviews and perspectives
Friston
K, Adams R and Montague R.
What is valueaccumulated reward or evidence?
Front. Neurorobot.
(2012) 6:11. doi:
10.3389/fnbot.2012.00011 - pdf
Edwards MJ, Adams
RA, Brown H, Pareιs I, Friston KJ.
A Bayesian account of 'hysteria'
Brain. 2012 May
28. [Epub ahead of print] - pdf
Friston K.
What is optimal about motor control?
Neuron. 2011 Nov
3;72(3):488-98. - pdf
Friston K.
The free-energy principle: a unified brain theory?
Nat Rev Neurosci.
2010 Feb;11(2):127-38. pdf
Friston K.
The free-energy principle: a rough guide to the brain?
Trends Cogn Sci.
2009 Jun 24.
pdf
Friston K.
Embodied Inference: or I think therefore I am, if I am what I think
In: The
Implications of Embodiment (Cognition and Communication) Eds. Wolfgang
Tschacher and Claudia Bergomi
Imprint Academic
ISBN 9781845402402 pdf
Technical papers
Friston K, Breakspear
M and Deco G
Perception and self-organized instability.
Front. Comput.
Neurosci. (2012) 6:44. doi:
10.3389/fncom.2012.00044 pdf
Friston K, Stephan
K, Li B, and Daunizeau J.
Generalised Filtering
Mathematical
Problems in Engineering. vol. 2010, Article ID 621670, 34 pages, 2010. pdf
Friston KJ.
Variational filtering.
Neuroimage. 2008
Jul 1;41(3):747-66. pdf
Friston KJ,
Trujillo-Barreto N, Daunizeau J.
DEM: A variational treatment of dynamic systems.
Neuroimage. 2008
Jul 1;41(3):849-85. pdf
Friston K, Mattout
J, Trujillo-Barreto N, Ashburner J, Penny W.
Variational free energy and the Laplace approximation.
NeuroImage. 2007
Jan 1;34(1):220-34. pdf
Features, commentaries and popular science
Friston KJ, Lawson R, Frith CD.
On
hyperpriors and hypopriors: comment on Pellicano and Burr.
Trends Cogn Sci.
2013 Jan;17(1):1 pdf
Friston K.
Competitive dynamics in the brain: Comment on "Information flow
dynamics in the brain" by M.I. Rabinovich et al.
Phys Life Rev. 2012
Mar;9(1):76-7 pdf
Friston K,
Predictive coding,
precision and synchrony
Cognitive Neuroscience. 2012. Volume 3, Issue
3-4:238-239 pdf
Friston K, Thornton C, Clark A.
Free-energy
minimization and the dark-room problem.
Front Psychol. 2012;3:130. pdf
Friston K.
Prediction,
perception and agency.
Int J Psychophysiol. 2012. 83:248-252 - pdf
Friston K.
The history of the future of the Bayesian brain.
Neuroimage. 2011
Oct 17 pdf
Is this a unified theory of the brain? From New
Scientist. 28 May 2008 pp 30-33 pdf
By Gregory T.
Huang
The Prophetic Brain: Universe in 2009 SEED Magazine pdf
By Karl Friston /
January 27, 2009
Surprise yourself. The Social Brain RSA. July 15, 2009 pdf
By Matt Grist
Thornton C.
Some puzzles relating to the free-energy
principle: comment on Friston.
Trends Cogn Sci. 2010 Feb;14(2):53-4; author reply 54-5. pdf
Friston K.
Is the free-energy principle neurocentric?
Nat Rev Neurosci. 2010 11:605 pdf
TV Interview (Spanish and
English)
Redes - La
fσrmula del cerebro (V.O.)
released: 20 November 2011
Lecture (for schoolchildren)
Brain
Awareness Week at the European Parliament
published: March. 19, 2010, recorded: March 2008
Free-energy and the brain (PowerPoint)
Lecture (for grownups)
Free energy and active inference
author: Karl Friston, Wellcome Trust Centre for
Neuroimaging, University College London
published: Oct. 16, 2012, recorded: September 2012
Theoretical neurobiology
Kiebel
SJ, Friston KJ.
Free energy and dendritic
self-organization.
Front
Syst Neurosci. 2011;5:80. pdf
Brown H, Friston
K, Bestamnn S.
Active inference, attention and motor preparation.
Front
Pyshcology 2:218. doi: 10.3389/fpsyg.2011.00218 pdf
Kiebel SJ, von
Kriegstein K, Daunizeau J, Friston KJ.
Recognizing sequences of sequences.
PLoS Comput Biol.
2009 Aug;5(8):e1000464. pdf
Friston K.
Learning and inference in the brain.
Neural Netw. 2003
Nov;16(9):1325-52. pdf
Friston K. Functional integration and inference in the brain.
Prog Neurobiol. 2002 Oct;68(2):113-43. pdf
Friston KJ. Brain function nonlinear coupling and neuronal transients.
Neuroscientist. 2001 Oct;7(5):406-18. pdf Friston KJ, Price CJ. Dynamic representations and generative models of brain function.
Brain Res Bull. 2001 Feb;54(3):275-85. pdf Friston KJ. The labile brain. I. Neuronal transients and nonlinear coupling. Philos Trans R Soc Lond B Biol Sci. 2000 Feb 29;355(1394):215-36. pdf Friston KJ. The labile brain. II. Transients, complexity and selection. Philos Trans R Soc Lond B Biol Sci. 2000 Feb 29;355(1394):237-52. pdf Friston KJ. The labile brain. III. Transients and spatio-temporal receptive fields.
Philos Trans R Soc Lond B Biol Sci. 2000 Feb 29;355(1394):253-65. pdf Friston KJ. Another neural code? NeuroImage. 1997 Apr;5(3):213-20. pdf Friston KJ. Transients, metastability, and neuronal dynamics.
NeuroImage. 1997 Feb;5(2):164-71. pdf Friston KJ. Neuronal transients. Proc Biol Sci. 1995 Sep 22;261(1362):401-5. pdf Friston, K. J., Tononi, G., Sporns, O. and Edelman, G. M. Characterising the complexity of neuronal interactions. Hum. Brain Mapp., 1995 3: 302314. pdf Predictive
coding and information theory
Brown HR, Friston
KJ.
Dynamic causal modelling of precision and synaptic gain in visual
perception - an EEG study.
Neuroimage. 2012
Oct 15;63(1):223-31 pdf
Coste CP,
Sadaghiani S, Friston KJ, and Kleinschmidt A.
Ongoing Brain Activity Fluctuations Directly Account for Intertrial and
Indirectly for Intersubject Variability in Stroop Task Performance
Cerebral Cortex
doi:10.1093/cercor/bhr050 pdf
Hesselmann G,
Sadaghiani S, Friston KJ, Kleinschmidt A.
Predictive coding or evidence accumulation? False inference and neuronal
fluctuations.
PLoS One. 2010 Mar
29;5(3):e9926 pdf
Friston KJ, Kiebel
SJ.
Attractors in song.
New Math. Nat.
Comput. 2009 5:83114. pdf
Friston KJ, Kiebel
SJ.
Cortical circuits for perceptual inference.
Neural Netw. 2009
Jul 19. [Epub ahead of print] pdf
Friston KJ, Kiebel
SJ.
Predictive coding under the free-energy principle
Phil. Trans. R.
Soc. B May 12, 2009 364:1211-1221 pdf
Brodersen KH,
Penny WD, Harrison LM, Daunizeau J, Ruff CC, Duzel E, Friston KJ, Stephan KE.
Integrated Bayesian models of learning and decision making for saccadic
eye movements.
Neural Netw. 2008
Nov;21(9):1247-60. pdf
Garrido MI, Kilner
JM, Kiebel SJ, Friston KJ.
Evoked brain responses are generated by feedback loops.
Proc Natl Acad Sci
U S A. 2007 Dec 26;104(52):20961-6. pdf
Furl N, van
Rijsbergen NJ, Treves A, Friston KJ, Dolan RJ.
Experience-dependent coding of facial expression in superior temporal
sulcus.
Proc Natl Acad Sci
U S A. 2007 Aug 7; pdf
Griffiths TD,
Kumar S, Warren JD, Stewart L, Stephan KE, Friston KJ.
Approaches to the cortical analysis of auditory objects.
Hear Res. 2007
Jul;229(1-2):46-53. Epub 2007 Jan 16. pdf
Kilner JM, Friston
KJ, Frith CD.
Predictive coding: an account of the mirror neuron system.
Cogn Process. 2007
Sep;8(3):159-66. pdf
Kilner JM, Friston
KJ, Frith CD.
The mirror-neuron system: a Bayesian perspective.
Neuroreport. 2007
Apr 16;18(6):619-23.
Harrison LM,
Stephan KE, Rees G, Friston KJ.
Extra-classical receptive field effects measured in striate cortex with
fMRI.
NeuroImage. 2007
Feb 1;34(3):1199-208. pdf
Harrison LM,
Duggins A, Friston KJ.
Encoding uncertainty in the hippocampus.
Neural Netw. 2006
Jun;19(5):535-46. pdf
Strange BA, Duggins A, Penny W, Dolan RJ, Friston KJ. Information theory, novelty and hippocampal responses: unpredicted or unpredictable? Neural Netw. 2005 Apr;18(3):225-30. pdf Computational
neuroscience
Marreiros AC,
Kiebel SJ, Daunizeau J, Harrison LM, Friston KJ.
Population dynamics under the Laplace assumption.
Neuroimage. 2009
Feb 1;44(3):701-14. pdf
Marreiros AC,
Daunizeau J, Kiebel SJ, Friston KJ.
Population dynamics: Variance and the sigmoid activation function.
NeuroImage. 2008
Apr 29 pdf
Chumbley JR, Dolan
RJ, Friston KJ.
Attractor models of working memory and their modulation by reward.
Biol Cybern. 2008
Jan;98(1):11-8. pdf
David O, Kilner
JM, Friston KJ.
Mechanisms of evoked and induced responses in MEG/EEG.
NeuroImage. 2006
Jul 15;31(4):1580-91. pdf
Harrison LM, David O, Friston KJ. Stochastic models of neuronal dynamics. Philos Trans R Soc Lond B Biol Sci. 2005 May 29;360(1457):1075-91. pdf
David O, Harrison L, Friston KJ. Modelling event-related responses in the brain. NeuroImage. 2005 Apr 15;25(3):756-70. pdf David O, Cosmelli D, Friston KJ. Evaluation of different measures of functional connectivity using a neural mass model. NeuroImage. 2004 Feb;21(2):659-73. pdf Breakspear M, Terry JR, Friston KJ. Modulation of excitatory synaptic coupling facilitates synchronization and complex dynamics in a biophysical model of neuronal dynamics. Network. 2003 Nov;14(4):703-32. pdf David O, Friston KJ. A neural mass model for MEG/EEG: coupling and neuronal dynamics. NeuroImage. 2003 Nov;20(3):1743-55. pdf Chawla D, Friston KJ, Lumer ED. Zero-lag synchronous dynamics in triplets of interconnected cortical areas. Neural Netw. 2001 Jul-Sep;14(6-7):727-35. pdf Chawla D, Lumer
ED, Friston KJ
Relating macroscopic measures of brain activity to fast, dynamic
neuronal interactions
Neural Computation
12, 2805-2821 (200) - pdf
. Rees G, Friston K, Koch C. A direct quantitative relationship between the functional properties of human and macaque V5. Nat Neurosci. 2000 Jul;3(7):716-23. (pdf) Chawla D, Lumer ED, Friston KJ. The relationship between synchronization among neuronal populations and their mean activity levels.
Neural Comput.
1999 Aug 15;11(6):1389-411. - pdf
Friston KJ Stephan KM Frackowiak RSJ Transient phase-locking and dynamic correlations: Are they the same thing? Human Brain Mapping 1997;5:48-57. - pdf Friston KJ, Frith CD, Frackowiak RS. Principal component analysis learning algorithms: a neurobiological analysis. Proc Biol Sci. 1993 Oct 22;254(1339):47-54. - pdf Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Investigating a network model of word generation with positron emission tomography. Proc Biol Sci. 1991 May 22;244(1310):101-6. - pdf
Dynamic
Causal Modelling
Seghier ML, Friston KJ.
Network discovery with large DCMs.
Neuroimage. 2012 68 (2013) 181191. - pdf
Pinotsis DA, Moran
RJ, Friston KJ.
Dynamic causal modeling with neural fields.
Neuroimage. 2012
Jan 16;59(2):1261-74. - pdf
Friston KJ, Bastos
A, Litvak V, Stephan KE, Fries P, Moran RJ.
DCM for complex-valued data: cross-spectra, coherence and phase-delays.
Neuroimage. 2012
Jan 2;59(1):439-55. - pdf
Moran RJ, Stephan
KE, Dolan RJ, Friston KJ.
Consistent spectral predictors for dynamic causal models of steady-state
responses.
Neuroimage. 2011
Apr 15;55(4):1694-708. - pdf
Havlicek M,
Friston KJ, Jan J, Brazdil M, Calhoun VD.
Dynamic modeling of neuronal responses in fMRI using cubature Kalman
filtering.
Neuroimage. 2011
Jun 15;56(4):2109-28. - pdf
Friston KJ, Li B,
Daunizeau J, Stephan KE.
Network discovery with DCM.
Neuroimage. 2010
Dec 21. - pdf
Li B, Daunizeau J,
Stephan KE, Penny W, Hu D, Friston K.
Generalised filtering and stochastic DCM for fMRI.
Neuroimage. 2011
Feb 16. - pdf
Marreiros AC,
Kiebel SJ, Friston KJ.
A dynamic causal model study of neuronal population dynamics.
Neuroimage. 2010
May 15;51(1):91-101.- pdf
Stephan KE, Penny
WD, Moran RJ, den Ouden HE, Daunizeau J, Friston KJ.
Ten simple rules for dynamic causal modeling.
Neuroimage. 2010
Feb 15;49(4):3099-109. - pdf
Penny WD, Litvak V, Fuentemilla L, Duzel E,
Friston K.
Dynamic
Causal Models for phase coupling.
J Neurosci
Methods. 2009 Sep 30;183(1):19-30. - pdf
Daunizeau J, Kiebel SJ, Friston KJ.
Dynamic
causal modelling of distributed electromagnetic responses.
Neuroimage. 2009
Aug 15;47(2):590-601. - pdf
Chen CC, Henson
RN, Stephan KE, Kilner JM, Friston KJ.
Forward and backward connections in the brain: a DCM study of functional
asymmetries.
Neuroimage. 2009
Apr 1;45(2):453-62 - pdf
Moran RJ, Stephan KE, Seidenbecher T, Pape
HC, Dolan RJ, Friston KJ.
Dynamic
causal models of steady-state responses.
Neuroimage. 2009
Feb 1;44(3):796-811. - pdf
Stephan KE, Kasper
L, Harrison LM, Daunizeau J, den Ouden HE, Breakspear M, Friston KJ.
Nonlinear dynamic causal models for fMRI.
Neuroimage. 2008
May 11 - pdf
Moran RJ, Stephan
KE, Kiebel SJ, Rombach N, O'Connor WT, Murphy KJ, Reilly RB, Friston KJ.
Bayesian estimation of synaptic physiology from the spectral responses
of neural masses.
Neuroimage. 2008
Feb 1. [Epub ahead of print] - pdf
Chen CC, Kiebel
SJ, Friston KJ.
Dynamic causal modelling of induced responses.
Neuroimage. 2008
Jul 15;41(4):1293-312. - pdf
Marreiros AC,
Kiebel SJ, Friston KJ.
Dynamic causal modelling for fMRI: a two-state model.
Neuroimage. 2008
Jan 1;39(1):269-78. - pdf
Stephan KE,
Weiskopf N, Drysdale PM, Robinson PA, Friston KJ.
Comparing hemodynamic models with DCM.
NeuroImage. 2007
Nov 15;38(3):387-401 - pdf
Garrido MI, Kilner
JM, Kiebel SJ, Stephan KE, Friston KJ.
Dynamic causal modelling of evoked potentials: A reproducibility study.
NeuroImage. 2007
Mar 27; [Epub ahead of print] pdf
Kiebel SJ, Garrido
MI, Friston KJ.
Dynamic causal modelling of evoked responses: The role of intrinsic
connections.
NeuroImage. 2007
Jun;36(2):332-45. pdf
Stephan
KE, Harrison LM, Kiebel SJ, David O, Penny WD, Friston KJ.
Dynamic causal models of neural system dynamics: current state and
future extensions.
J
Biosci. 2007 Jan;32(1):129-44.
Kiebel SJ, Kloppel
S, Weiskopf N, Friston KJ.
Dynamic causal modeling: a generative model of slice timing in fMRI.
NeuroImage. 2007
Feb 15;34(4):1487-96. pdf
Mouridsen K,
Friston K, Hjort N, Gyldensted L, Ostergaard L, Kiebel S.
Bayesian estimation of cerebral perfusion using a physiological model of
microvasculature.
NeuroImage. 2006 Nov
1;33(2):570-9. pdf
Kiebel SJ, David
O, Friston KJ.
Dynamic causal modelling of evoked responses in EEG/MEG with lead field
parameterization.
NeuroImage. 2006
May 1;30(4):1273-84. pdf
David O, Kiebel
SJ, Harrison LM, Mattout J, Kilner JM, Friston KJ.
Dynamic causal modeling of evoked responses in EEG and MEG.
NeuroImage. 2006
May 1;30(4):1255-72. pdf
Stephan KE, Penny
WD, Marshall JC, Fink GR, Friston KJ.
Investigating the functional role of callosal connections with dynamic
causal models.
Ann N Y Acad Sci.
2005 Dec;1064:16-36.
Lee L, Friston K,
Horwitz B.
Large-scale neural models and dynamic causal modelling.
NeuroImage. 2006
May 1;30(4):1243-54. pdf
Penny WD, Stephan KE, Mechelli A, Friston KJ. Comparing dynamic causal models.NeuroImage. 2004 Jul;22(3):1157-72. pdf
Penny WD, Stephan KE, Mechelli A, Friston KJ. Modelling functional integration: a comparison of structural equation and dynamic causal models. NeuroImage. 2004;23 Suppl 1:S264-74. pdf
Mechelli A, Price CJ, Noppeney U, Friston KJ. A dynamic causal modeling study on category effects: bottom-up or top-down mediation? J Cogn Neurosci. 2003 Oct 1;15(7):925-34.
Friston KJ, Harrison L, Penny W. Dynamic causal modelling.
NeuroImage. 2003 Aug;19(4):1273-302. pdf Bayesian
and Variational model inversion
Balaji B, and Karl
Friston K.
Bayesian state estimation using generalized coordinates.
Proc. SPIE 8050,
80501Y (2011) pdf
Friston K, Penny
W.
Post hoc Bayesian model selection.
Neuroimage. 2011
Jun 15;56(4):2089-99..
pdf
Friston K, Stephan
K, Li B, and Daunizeau J.
Generalised Filtering
Mathematical
Problems in Engineering. vol. 2010, Article ID 621670, 34 pages, 2010. pdf
Friston KJ.
Variational filtering.
Neuroimage. 2008
Jul 1;41(3):747-66. pdf
Friston KJ,
Trujillo-Barreto N, Daunizeau J.
DEM: A variational treatment of dynamic systems.
Neuroimage. 2008
Jul 1;41(3):849-85. pdf
Friston K, Mattout
J, Trujillo-Barreto N, Ashburner J, Penny W.
Variational free energy and the Laplace approximation.
NeuroImage. 2007
Jan 1;34(1):220-34. pdf
Penny W, Ghahramani Z, Friston K Bilinear dynamical systems. Philos Trans R Soc Lond B Biol Sci. 2005 May 29;360(1457):983-93. pdf Penny WD, Trujillo-Barreto NJ, Friston KJ. Bayesian fMRI time series analysis with spatial priors. NeuroImage. 2005 Jan 15;24(2):350-62. pdf Harrison L, Penny WD, Friston K. Multivariate autoregressive modeling of fMRI time series. NeuroImage. 2003 Aug;19(4):1477-91. pdf Penny W, Kiebel S, Friston K. Variational Bayesian inference for fMRI time series. NeuroImage. 2003 Jul;19(3):727-41. pdf Friston KJ, Penny
W
Posterior probability maps and SPMs
NeuroImage, (2003)
19, 1240-1249. pdf
Phillips C, Rugg MD, Friston KJ. Anatomically informed basis functions for EEG source localization: combining functional and anatomical constraints. NeuroImage. 2002 Jul;16(3 Pt 1):678-95. pdf Friston KJ
Bayesian Estimation of Dynamical Systems: An Application to fMRI
NeuroImage 16,
513-530 (2002) pdf
Friston KJ, Penny
W, Phillips, Kiebel S, Hinton G, Ashburner J
Classical and
Bayesian Inference in Neuroimaging: Theory
NeuroImage 16,
465-483 (2002) pdf
Friston KJ, Glaser
DE, Henson RNA, Kiebel S, Phillips C, Ashburner J
Classical and Bayesian Inference in Neuroimaging: Applications
NeuroImage 16,
484-512 (2002) pdf
Phillips C, Rugg MD & Friston KJ. Systematic Regularization of Linear Inverse Solutions of the EEG Source Localization Problem. NeuroImage 2002;17:287-301 pdf
Bόchel C, Friston KJ. Dynamic changes in effective connectivity characterized by variable parameter regression and Kalman filtering. Hum Brain Mapp. 1998;6(5-6):403-8. pdf Lecture
Variational
filtering in generated coordinates of motion
published: Sept. 9, 2008, recorded: May 2008
Variational filtering and DEM (PowerPoint)
Optimality,
value-learning and plasticity
Mathys C, Jean
Daunizeau J, Karl J Friston KJ, Klaas Enno Stephan KE.
A Bayesian foundation for individual learning under uncertainty
Front. Hum.
Neurosci. 5:35 DOI: 10.3389/fnhum.2011.00039 pdf
Daunizeau J, den
Ouden HE, Pessiglione M, Kiebel SJ, Stephan KE, Friston KJ.
Observing the observer (I): meta-bayesian models of learning and
decision-making.
PLoS One. 2010 Dec
14;5(12):e15554. pdf
Daunizeau J, den
Ouden HE, Pessiglione M, Kiebel SJ, Friston KJ, Stephan KE.
Observing the observer (II): deciding when to decide.
PLoS One. 2010 Dec
14;5(12):e15555. pdf
Garrido MI, Kilner
JM, Kiebel SJ, Stephan KE, Baldeweg T, Friston KJ.
Repetition suppression and plasticity in the human brain.
Neuroimage. 2009
Oct 15;48(1):269-79. pdf
Yoshida W, Dolan RJ, Friston KJ.Game theory of mind.
PLoS Comput Biol. 2008 Dec;4(12):e1000254. pdf Seymour B, O'Doherty JP, Dayan P, Koltzenburg M, Jones AK, Dolan RJ, Friston KJ, Frackowiak RS. Temporal difference models describe higher-order learning in humans. Nature. 2004 Jun 10;429(6992):664-7. pdf O'Doherty J, Dayan P, Schultz J, Deichmann R, Friston K, Dolan RJ. Dissociable roles of ventral and dorsal striatum in instrumental conditioning. Science. 2004 Apr 16;304(5669):452-4. O'Doherty JP, Dayan P, Friston K, Critchley H, Dolan RJ. Temporal difference models and reward-related learning in the human brain. Neuron. 2003 Apr 24;38(2):329-37. pdf Thiel CM, Friston KJ, Dolan RJ. Cholinergic modulation of experience-dependent plasticity in human auditory cortex. Neuron. 2002 Aug 1;35(3):567-74. pdf Elliott R, Friston KJ, Dolan RJ. Dissociable neural responses in human reward systems. J Neurosci. 2000 Aug 15;20(16):6159-65. Bόchel C, Coull JT, Friston KJ. The predictive value of changes in effective connectivity for human learning. Science. 1999 Mar 5;283(5407):1538-41. pdf Friston KJ, Tononi G, Reeke GN Jr, Sporns O, Edelman GM. Value-dependent selection in the brain: simulation in a synthetic neural model. Neuroscience. 1994 Mar;59(2):229-43. pdf Dysconnection
hypothesis and schizophrenia
Adams RA, Perrinet
LU, Friston K.
Smooth pursuit and visual occlusion: active inference and oculomotor
control in schizophrenia.
PLoS One. 2012;7(10):e47502 pdf
Stephan KE, Karl
J. Friston KJ, Frith CD
Dysconnection in Schizophrenia: From Abnormal Synaptic Plasticity to
Failures of Self-monitoring
Schizophrenia
Bulletin 2009; doi: 10.1093/schbul/sbn176
pdf
Stephan KE,
Baldeweg T, Friston KJ.
Synaptic plasticity and dysconnection in schizophrenia.
Biol Psychiatry.
2006 May 15;59(10):929-39. Epub 2006 Jan 19. Review pdf
Friston KJ.
Hallucinations and perceptual inference
Behavioral and
Brain Sciences [0140-525X]: 2005 28(6):764-766 pdf
Friston KJ Disconnection and cognitive dysmetria in schizophrenia. Am J Psychiatry. 2005 Mar;162(3):429-32. pdf
Friston KJ. Dysfunctional connectivity in schizophrenia. World Psychiatry. 2002 Jun;1(2):66-71. pdf Friston KJ. Schizophrenia and the disconnection hypothesis. Acta Psychiatr Scand Suppl. 1999;395:68-79. Friston KJ. The disconnection hypothesis. Schizophr Res. 1998 Mar 10;30(2):115-25. pdf Friston KJ. Theoretical neurobiology and schizophrenia. Br Med Bull. 1996 Jul;52(3):644-55. pdf
Friston KJ, Frith CD. Schizophrenia: a disconnection syndrome? Clin Neurosci. 1995;3(2):89-97. pdf
Degeneracy
Noppeney U, Friston KJ, Price CJ. Degenerate neuronal systems sustaining cognitive functions. J Anat. 2004 Dec;205(6):433-42. Friston KJ, Price CJ. Degeneracy and redundancy in cognitive anatomy. Trends Cogn Sci. 2003 Apr;7(4):151-152. pdf Price CJ, Friston KJ. Degeneracy and cognitive anatomy. Trends Cogn Sci. 2002 Oct 1;6(10):416-421. pdf Price CJ, Mummery CJ, Moore CJ, Frackowiak RS, Friston KJ. Delineating necessary and sufficient neural systems with functional imaging studies of neuropsychological patients. J Cogn Neurosci. 1999 Jul;11(4):371-82. Neuroimaging
(reviews and commentaries)
Friston K, Moran
R, Seth AK.
Analysing connectivity with Granger
causality and dynamic causal modelling.
Curr Opin Neurobiol. 2012 Dec 21. doi:pii: S0959-4388(12)00184-5.
pdf
Friston K.
Ten ironic rules for non-statistical reviewers.
Neuroimage. 2012
61: 13001310 pdf
Friston KJ.
Functional and Effective Connectivity: A Review
Brain Connectivity.
2011, 1(1): 13-36. pdf
Friston KJ, Dolan
RJ.
Computational and dynamic models in neuroimaging.
Neuroimage. 2009
Dec 28. [Epub ahead of print] pdf
Friston KJ.
Modalities, modes, and models in functional neuroimaging.
Science. 2009 Oct
16;326(5951):399-403. pdf
Kiebel SJ, Garrido
MI, Moran R, Chen CC, Friston KJ.
Dynamic causal modeling for EEG and MEG.
Hum Brain Mapp.
2009 Jun;30(6):1866-76. Review. pdf
Friston K.
Causal modelling and brain connectivity in functional magnetic resonance
imaging.
PLoS Biol. 2009
Feb 17;7(2):e33. pdf
Friston KJ,
Rotshtein P, Geng JJ, Sterzer P, Henson RN.
A critique of functional localisers.
NeuroImage. 2006
May 1;30(4):1077-87. pdf
Friston KJ.
Models of brain function in neuroimaging.
Annu Rev Psychol.
2005;56:57-87 pdf
Friston K. Beyond phrenology: what can neuroimaging tell us about distributed circuitry? Annu Rev Neurosci. 2002;25:221-50. Epub 2002 Mar 19. pdf Friston KJ.Imaging neuroscience: principles or maps?Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):796-802 pdf
Friston KJ, Price CJ, Fletcher P, Moore C, Frackowiak RS, Dolan RJ. The trouble with cognitive subtraction. NeuroImage. 1996 Oct;4(2):97-104. pdf Friston KJ Functional and effective connectivity in neuroimaging: A synthesis Human Brain Mapping 1995: 2;56-78 pdf Friston KJ, Frith CD, Passingham RE, Liddle PF, Frackowiak RS.Motor practice and neurophysiological adaptation in the cerebellum: a positron tomography study.Proc Biol Sci. 1992 Jun 22;248(1323):223-8 pdf Voxel-based
morphometry and computational anatomy
Ashburner J, Friston KJ. Unified segmentation. NeuroImage. 2005 Jul 1;26(3):839-51. pdf Friston KJ, Ashburner J. Generative and recognition models for neuroanatomy. NeuroImage. 2004 Sep;23(1):21-4. Salmond CH, Ashburner J, Vargha-Khadem F, Connelly A, Gadian DG, Friston KJ. Distributional assumptions in voxel-based morphometry. NeuroImage. 2002 Oct;17(2):1027-30. pdf Ashburner J, Friston KJ. Voxel-based morphometry--the methods.
NeuroImage. 2000 Jun;11(6 Pt 1):805-21. pdf Wright IC, McGuire PK, Poline JB, Travere JM, Murray RM, Frith CD, Frackowiak RS, Friston KJ. A voxel-based method for the statistical analysis of gray and white matter density applied to schizophrenia. NeuroImage. 1995 Dec;2(4):244-52. pdf Friston KJ Ashburner J Frith CD Poline J-B Heather JD and Frackowiak RSJ The spatial registration and normalisation of images pdf
Human Brain Mapping 1995;3:165-189 Friston KJ, Passingham RE, Nutt JG, Heather JD, Sawle GV, Frackowiak RS. Localisation in PET images: direct fitting of the intercommissural (AC-PC) line. J Cereb Blood Flow Metab. 1989 Oct;9(5):690-5. Hemodynamic
models
J.M. Kilner, J. Mattout, R. Henson and K.J. FristonHemodynamic correlates of EEG: A heuristicNeuroImage, Volume 28, Issue 1, 15 October 2005, Pages 280-286. pdf Mechelli A, Price CJ, Friston KJ. Nonlinear coupling between evoked rCBF and BOLD signals: a simulation study of hemodynamic responses.
NeuroImage. 2001 Oct;14(4):862-72. pdf Friston KJ,
Mechelli A, Turner R, Price CJ
Nonlinear
Responses in fMRI: The Balloon Model, Volterra Kernels and Other Hemodynamics
NeuroImage 12,
466-477 (2000) pdf
Friston KJ, Josephs O, Rees G, Turner R. Nonlinear event-related responses in fMRI. Magn Reson Med. 1998 Jan;39(1):41-52. pdf K.J. Friston, P. Jezzard, and R. Turner
Analysis of Functional MRI Time-Series
Human Brain Mapping 1:153-171(1994) pdf
Friston KJ
Regulation
of rCBF by Diffusible Signals: An Analysis of Constraints on Diffusion and
Elimination
Human Brain
Mapping 3:56-65(1995) pdf
Multivariate
models
Friston K, Chu C, Mourγo-Miranda J, Hulme O, Rees G, Penny W, Ashburner J.Bayesian decoding of brain images.Neuroimage. 2007 Aug 24. pdf Friston K, Phillips J, Chawla D, Bόchel C. Nonlinear PCA: characterizing interactions between modes of brain activity.
Philos Trans R Soc Lond B Biol Sci. 2000 Jan 29;355(1393):135-46. pdf Friston KJ, Frith CD, Fletcher P, Liddle PF, Frackowiak RS.Functional topography: multidimensional scaling and functional connectivity in the brain.Cereb Cortex. 1996 Mar-Apr;6(2):156-64. pdf
Friston KJ, Frith CD, Frackowiak RS, Turner R.
Characterizing dynamic brain responses with fMRI: a multivariate approach.
Neuroimage. 1995 Jun;2(2):166-72. pdf
Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Functional connectivity: the principal-component analysis of large (PET) data sets. J Cereb Blood Flow Metab. 1993 Jan;13(1):5-14. pdf K.J. Friston, L.G. Ungerleider, P. Jezzard, and R. Turner.Characterizing modulatory interactions between V1 and V2 in human cortex with fMRIHuman Brain Mapping, 2:211-224, 1995. - pdf Topological
inference
Chumbley J, Worsley K, Flandin G, Friston K.Topological FDR for neuroimaging.Neuroimage. 2010 Feb 15;49(4):3057-64. pdf Friston KJ. Testing for anatomically specified regional effects. Hum Brain Mapp. 1997;5(2):133-6. pdf Friston KJ, Holmes A, Poline JB, Price CJ, Frith CD. Detecting activations in PET and fMRI: levels of inference and power. NeuroImage. 1996 Dec;4(3 Pt 1):223-35. pdf Worsley KJ Marrett S Neelin P Vandal AC Friston KJ Evans AC A unified statistical approach for determining significant signals in images of cerebral activation Human Brain Mapping 1996;4:58-73. pdf Friston KJ Holmes
AP Worsley KJ Poline JB Frith CD and Frackowiak RSJ
Statistical Parametric Maps in functional imaging: A general linear
approach
Human Brain
Mapping 1995;2;189-210. pdf
Friston KJ Worsley KJ Frackowiak RSJ Mazziotta JC & Evans AC Assessing the significance of focal activations using their spatial extent Human Brain Mapping 1994;1:214-220. pdf Friston KJ, Frith CD, Liddle PF, Frackowiak RS. Comparing functional (PET) images: the assessment of significant change. J Cereb Blood Flow Metab. 1991 Jul;11(4):690-9. pdf Friston KJ, Frith CD, Liddle PF, Dolan RJ, Lammertsma AA, Frackowiak RS. The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab. 1990 Jul;10(4):458-66. pdf Source
reconstruction (EEG and MEG)
Litvak V, Friston K.Electromagnetic source reconstruction for group studies.Neuroimage. 2008 Oct 1;42(4):1490-8. - pdf Friston K, Harrison L, Daunizeau J, Kiebel S, Phillips C, Trujillo-Barreto N, Henson R, Flandin G, Mattout J.Multiple sparse priors for the M/EEG inverse problem.Neuroimage. 2007 Oct 10; [Epub ahead of print] pdf Mattout, J., Henson, R N. & Friston, K.J. Canonical Source Reconstruction for MEG.Computational Intelligence and Neuroscience. 2007. Article ID 67613 pdf Daunizeau J,
Friston KJ.
A mesostate-space model for EEG and MEG.
NeuroImage. 2007
Jul 24;38(1):67-81 pdf
Friston K, Henson
R, Phillips C, Mattout J.
Bayesian estimation of evoked and induced responses.
Hum Brain Mapp.
2006 Feb 1;27(9):722-735. pdf
Mattout J,
Phillips C, Penny WD, Rugg MD, Friston KJ.
MEG source localization under multiple constraints: An extended Bayesian
framework.
NeuroImage. 2005
Dec 17; [Epub ahead of print] pdf
Phillips C, Mattout J, Rugg MD, Maquet P, Friston KJ. An empirical Bayesian solution to the source reconstruction problem in EEG. NeuroImage. 2005 Feb 15;24(4):997-1011. pdf
Recent Presentations
Dynamic Causal Modelling (PowerPoint)
Free-energy and the brain (PowerPoint)
Free-energy and value (PowerPoint)
Cortical connectivity (PowerPoint)
Variational filtering and DEM (PowerPoint)
Free-energy
lecture (PowerPoint)
Movie files
Sensor space - movie
Source space - movie
Boulders - movie
Starlings - movie
Smile (stimulus) - movie
Smile (percept) - movie
Reaching movement - movie
Mountain car - movie
Simulated creatures (by Karl Sims) - movie
Curriculum Vitae - doc